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09/2014   Direct comparison of targeted MRI-guided biopsy with systematic transrectal ultrasound-guided biopsy in patients with previous negative prostate biopsies. Kaufmann S, Kruck S, Kramer U, Gatidis S, Stenzl A, Roethke M, Scharpf M, Schilling D.
OBJECTIVE: To directly compare the diagnostic performance of targeted MRI-guided biopsy (MR-GB) and systematic transrectal ultrasound-guided biopsy (TRUS-GB).
  pdf Document
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08/2014   Trocar-sharpened needles for image-guided prostate biopsy improve sample quality and performance: first clinical results. Simpfendörfer T, Kuru TH, Steinemann S, Bergsträsser C, Block S, Roth W, Roethke MC, Hohenfellner M, Hadaschik BA.
OBJECTIVE: To show the benefit of trocar-sharpened needles for image-guided prostate biopsy compared with standard bevelled needles in patients.
  pdf Document
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08/2014   Evolution of repeat prostate biopsy strategies incorporating transperineal and MRI-TRUS fusion techniques. Kuru TH1, Saeb-Parsy K, Cantiani A, Frey J, Lombardo R, Serrao E, Gaziev G, Koo B, Roethke M, Gnanapragasam V, Warren A, Doble A, Hadaschik B, Kastner C.
PURPOSE: To test the hypothesis that MRI-TRUS fusion technique can increase the detection rate of prostate cancer (PC) in patients with previously negative biopsy.
  pdf Document
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04/2014   Prostate cancer: performance characteristics of combined T₂W and DW-MRI scoring in the setting of template transperineal re-biopsy using MR-TRUS fusion. Lawrence EM, Tang SY, Barrett T, Koo B, Goldman DA, Warren AY, Axell RG, Doble A, Gallagher FA, Gnanapragasam VJ, Kastner C, Sala E.
OBJECTIVES: To measure the performance characteristics of combined T2-weighted (T₂W) and diffusion-weighted (DW) magnetic resonance imaging (MRI) suspicion scoring prior to MR-transrectal ultrasound (TRUS) fusion template transperineal (TTP) re-biopsy.
  pdf Document
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04/2014   Evaluation of the ESUR PI-RADS scoring system for multiparametric MRI of the prostate with targeted MR/TRUS fusion-guided biopsy at 3.0 Tesla. Roethke MC, Kuru TH, Schultze S, Tichy D, Kopp-Schneider A, Fenchel M, Schlemmer HP, Hadaschik BA.
OBJECTIVES: To evaluate the Prostate Imaging Reporting and Data System (PI-RADS) proposed by the European Society of Urogenital Radiology (ESUR) for detection of prostate cancer (PCa) by multiparametric magnetic resonance imaging (mpMRI) in a consecutive cohort of patients with magnetic resonance/transrectal ultrasound (MR/TRUS) fusion-guided biopsy.
  pdf Document
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2014   Computer aided transperineal optimized prostate (TOP) biopsy for volumetric contour based biopsy core planning Popeneciu IV, Kuru TH, Zogal P, Boxler S, Hohenfellner M, Sakas G, Hadaschik BA
PURPOSE: To develop and evaluate an algorithm applicable in perineal navigated prostate biopsy to maximize cancer detection rates while minimizing numbers of cores. The calculations take into account the real-life 3D contours of the prostate, the topographic related risk of cancer in the different prostate regions, as well as a user selectable maximal clinically significant tumour volume, providing a unique per patient computer aided biopsy map for real-time targeting.
 
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2014   Optimized transperineal prostate biopsy computer algorithm (TOP) for volumetric contour based biopsy core planning Popeneciu. IV, Kuru TH, Zogal P, Boxler S, Hohenfellner M, Sakas G, Hadaschik BA PURPOSE: To develop and evaluate an algorithm applicable in perineal navigated prostate biopsy to maximize cancer detection rates while minimizing numbers of cores, as an alternative or supplement to multiparametric prostate MRI information. The calculations take into account the real-life 3D contours of the prostate (ultrasound or MRI based), the topographic related risk of cancer in the different prostate regions, as well as a user selectable maximal clinically significant tumour volume, providing a unique per patient computer aided biopsy map for real-time targeting.  
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2014   Computer aided transperineal optimized prostate (TOP) biopsy for volumetric contour based biopsy core planning. I.V.Popeneciu, J.P.Radtke, P.Zogal, S.Boxler, M.Hohenfellner, G.Sakas, B.A.Hadaschik
Introduction: We developed an algorithm applicable in perineal navigated prostate biopsy to maximize cancer detection rates. The TOP algorithm provides a computer aided visual guide for systematic organ targeting using the 3D prostate contour and a user selectable tumour volume to be excluded.
 
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