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12/2015   Investigating the ability of multiparametric MRI to exclude significant prostate cancer prior to transperineal biopsy. Serrao EM, Barrett T, Wadhwa K, Parashar D, Frey J, Koo BC, Warren AY, Doble A, Kastner C, Gallagher FA.
INTRODUCTION: We characterized false negative prostate magnetic resonance imaging (MRI) reporting by using histology derived from MRI-transrectal ultrasound (TRUS)-guided transperineal (MTTP) fusion biopsies.
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08/2015   Targeted transperineal biopsy of the prostate has limited additional benefit over background cores for larger MRI-identified tumors. Barrett T, Patterson AJ, Koo BC, Wadhwa K, Warren AY, Doble A, Gnanapragasam VJ, Kastner C, Gallagher FA.
PURPOSE: To compare histological outcomes in patients undergoing MRI-transrectal ultrasound fusion transperineal (MTTP) prostate biopsy and determine the incremental benefit of targeted cores.
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07/2015   Detection of Clinically Significant Prostate Cancer Using Magnetic Resonance Imaging-Ultrasound Fusion Targeted Biopsy: A Systematic Review. Valerio M1, Donaldson I2, Emberton M2, Ehdaie B3, Hadaschik BA4, Marks LS5, Mozer P6, Rastinehad AR7, Ahmed HU2.
CONTEXT: The current standard for diagnosing prostate cancer in men at risk relies on a transrectal ultrasound-guided biopsy test that is blind to the location of the cancer. To increase the accuracy of this diagnostic pathway, a software-based magnetic resonance imaging-ultrasound (MRI-US) fusion targeted biopsy approach has been proposed.
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06/2015   Improved detection of anterior fibromuscular stroma and transition zone prostate cancer using biparametric and multiparametric MRI with MRI-targeted biopsy and MRI-US fusion guidance. Radtke JP, Boxler S, Kuru TH, Wolf MB, Alt CD, Popeneciu IV, Steinemann S, Huettenbrink C, Bergstraesser-Gasch C, Klein T, Kesch C, Roethke M, Becker N, Roth W, Schlemmer HP, Hohenfellner M, Hadaschik BA.
BACKGROUND: The objective of this study was to analyze the potential of prostate magnetic resonance imaging (MRI) and MRI/transrectal ultrasound-fusion biopsies to detect and to characterize significant prostate cancer (sPC) in the anterior fibromuscular stroma (AFMS) and in the transition zone (TZ) of the prostate and to assess the accuracy of multiparametric MRI (mpMRI) and biparametric MRI (bpMRI) (T2w and diffusion-weighted imaging (DWI)).
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05/2015   Defining the learning curve for multiparametric magnetic resonance imaging (MRI) of the prostate using MRI-transrectal ultrasonography (TRUS) fusion-guided transperineal prostate biopsies as a validation tool.
Gaziev G, Wadhwa K, Barrett T, Koo BC, Gallagher FA, Serrao E, Frey J, Seidenader J, Carmona L, Warren A, Gnanapragasam V, Doble A, Kastner C.

Abstract: OBJECTIVES: To determine the accuracy of multiparametric magnetic resonance imaging (mpMRI) during the learning curve of radiologists using MRI targeted, transrectal ultrasonography (TRUS) guided transperineal fusion biopsy (MTTP) for validation.
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05/2015   “ONE-STOP-SHOPPING”: BIOPSY, DIAGNOSIS & FOCAL THERAPY IN ONE SESSION
I. Skalkidis, G. Sakas, U. Tunn

Introduction: Our purpose was to maximize efficiency and accuracy and minimize patient discomfort by combining prostate biopsy, pathology examination and, if necessary and indicated, (focal) CA-therapy in only one session. The whole procedure takes place under general anesthesia and lasts less than 2 hours. By means of mpMRI we pre-select low-risk, single lesion patients as candidates for such treatment. We then first perform prostate biopsy, then pathology, and last focal therapy of prostate CA location(s) using irreversible electroporation (IRE) without intermediate patient movement.
Abstract 43
 
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01/2015   Comparative analysis of transperineal template saturation prostate biopsy versus magnetic resonance imaging targeted biopsy with magnetic resonance imaging-ultrasound fusion guidance. Radtke JP1, Kuru TH2, Boxler S3, Alt CD4, Popeneciu IV1, Huettenbrink C1, Klein T1, Steinemann S1, Bergstraesser C1, Roethke M5, Roth W6, Schlemmer HP5, Hohenfellner M1, Hadaschik BA1.
PURPOSE: Multiparametric magnetic resonance imaging and magnetic resonance imaging targeted biopsy may improve the detection of clinically significant prostate cancer. However, standardized prospective evaluation is limited.
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