ProSoma Core®

Monte Carlo Based Dose QA

Based on proprietary, undisclosed MedCom technology

 

Radiation Oncology / ProSoma Core

ProSoma Core Simplifies Treatment Verification

ProSoma Core is a new software package for the verification of patient treatments in radiation oncology. It is designed to simplify your work and enhance the confidence in your treatment planning procedure. It also enables you to determine what a LINAC does and what the consequences are for the patient if the machine does not perform as expected.

Today’s radiation techniques like IMRT, VMAT and SBRT are getting more and more complex. At the same time, tolerances are getting smaller and smaller. Both trends lead to increased quality assurance efforts occupying machine and human resources. Classical verification techniques by measuring dose in phantoms are state of the art, but they cannot determine inaccuracies in the real human body. Furthermore these techniques are time consuming while an extensive machine QA has to be performed anyhow required and stipulated by law and authorities.

To solve this inherent conflict ProSoma Core provides you an alternative for your daily routine. The idea behind the product is not just a check of monitor units, it is a comprehensive verification of plans calculated by treatment planning systems.

Before Irradiation

  • Recalculate plan by an independent and ultra-accurate Monte Carlo engine
  • Compare & display deviations between desired and recalculated plans
  • Check plan stability, i.e. changes in dose distributions caused by patient movements

After Irradiation

  • Collect machine logfiles and compare planned fluence to delivered fluence
  • Use machine logfiles to recalculate the truly delivered 3D dose over all fractions
  • Make use of CBCT and correction matrix to recalculate dose on deformed anatom

Key Benefits Overview

  • Fully automatic 3D dose plan verification
  • High quality and fast Monte Carlo engine
  • Convenient review of PDF reports via web interface or notification via e-mail
  • Robustness analysis: calculate effects of spatial uncertainties
  • Recalculate plans based on machine logfiles
  • QA protocols customizable per treatment region
  • Interactive plan verification as an option
  • Definitive answers to not measurable effects in head&neck and chest regions
  • Usage of CBCT to take into account anatomical changes during treatment

Plan Recalculation

After automatic import of all patient related DICOM objects a newly designed Monte Carlo algorithm calculates dose distributions on standard CPU hardware within minutes with an overall uncertainty of less than 1%. Based on a set of customizable objectives including gamma and dose deviations, DVH based metrics, cross section images and others an immediate answer is given whether a plan is acceptable or weak. Furthermore, ProSoma Core verifies the robustness of treatment plans by applying the typical patient position variations and calculating their impact on the dose distribution. An interactive mode allows the detailed investigation of critical regions.

Machine Logfile Evaluation

In addition to the verification of treatment plans, ProSoma Core processes the machine logfiles provided by the LINAC which indicate actual leaf positions, collimator and gantry angles as well as dose rates. The software compares the fluence calculated from the treatment plan to the one derived from the logfiles. In case considerable deviations are detected, a full 3D dose calculation is performed to examine their implications for the DVH. Furthermore, all logfile data are internally recorded to enable you to generate an overall summary report after finalizing the treatment which calculates the truly delivered dose over all fractions and additionally contains evaluations of leaf pair and gantry angle deviations.

CBCT Monitor

ProSoma Core’s CBCT monitor covers another major source of 
inaccuracies in radiotherapy:

anatomical changes in the course of the treatment. For that purpose, the CBCT usually acquired before treatment is deformably registered to the planning CT to transfer all structures to the new anatomy.

Additionally, the correction matrix applied on the patient couch before treatment is taken into account to be able to correctly recalculate the 3D dose on the deformed anatomy.
This analysis per fraction is also accumulated over the complete treatment period to enable the assessment of DVH effects or volume changes over time.
The system may apply user defined metrics to compared to the accumulated DVH with the state that was originally planned in order to support a decision whether replanning is required or not. Beside the monitoring of biological effects the system may further compare the applied patient registration with an VOI based registration applied by ProSoma. The CBCT monitoring is a fully automatic process running in the background.

Web Interface

ProSoma Core comes with a web interface to enable you to conveniently access all evaluation results from any computer within your clinic network. The web interface presents all reports created by ProSoma Core, filtered with respect to creation date or report type, and whether they have passed or failed. Moreover it offers an option to approve reports, which is directly recorded in the respective PDF document. You can also configure the software to e-mail all verification results to a number of responsible persons for validation or to send them as embedded objects to your PACS.